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Needlestick injuries: Accidental work exposure
When health care workers are accidentally exposed to HIV on the job,
they are increasingly prescribed a cocktail of drugs similar to that used
to treat infected patients and, at least in the short term, often saved
from infection.
The
Centers for Disease Control and Prevention (CrD) reports that the combination
of drugs is effective as a so-called postexposure prophylaxis in 79 percent
of such cases if it is started within one or two hours of exposure.
The
CDC has, recommended that the treatment be given all health workers exposed
to HIV on the job. Other uses of the treatment are being considered, such
as HIV prevention for rape victims and intravenous drug users who have been
exposed to the vinus.
However,
the CDC is reluctant to extend the recommendations due to gaps in understanding
how HIV is transmitted and the side effects of the drugs.
Although
health care workers who are accidentally exposed to HIV on the job are routinely
offered antiviral drugs to reduce their risk of infection, this option is
not generally extended to people who are accidentally exposed to the virus
Health
officials are now considering expancling the treatment for certain sexual
exposures like when a condom breaks or exposure during rape.
David
Bell, chief of the HIV infections branch of the hospital infections program
at the Centers for Disease Control and Prevention, notes, "We get calls
from rape crisis centers, and the CDC AIDS hotline has been getting calls"
from people concemed about infection after possible exposure during a high
risk sexual encounter or when a condom breaks.
At
some San Francisco hospitals, health officials plan to offer the preventive
treatment starting this spring. The drugs are already offered to rape victims
in British Columbia's Women's Hospital.
After
an HIV exposure, the CDC currently recommends immediate treatment with a
combination of zidovudine (AZT) and lamivudine (3TC) (or in some cases indinavir).
Over
the coming months, the CDC will develop recommendations for preventive treatment
for some kinds of sexual exposure.
(CDC National AIDS Clearinghouse 1/14/97 and 2/4/97)
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